Paeonia Extract – Standardized, High-Purity, Skin-Soothing


Extract of Radix Paeoniae Alba: lab-grade calm for real-world formulas

If you work in nutraceuticals or indie skincare, you’ve probably bumped into
Paeonia Extract
at some point—usually praised for its soothing profile and that quietly famous marker compound, paeoniflorin. I’ve seen it cycle from niche TCM staple to mainstream actives lists, and, to be honest, it’s having a moment again. Supply is more predictable now, specs are cleaner, and brands are asking for tighter standardization. Origin here is clear too: NO.12, XIJIAN STREET, SHIJIAZHUANG CITY, HEBEI PROVINCE, CHINA.

Paeonia Extract

Industry trends (and a quick reality check)

Two currents stand out: 1) standardization toward ≥10% paeoniflorin by HPLC; 2) clean solvent demands (water/ethanol). Cosmetic labs lean into skin comfort claims; supplement brands favor women’s wellness blends. I guess what surprised me this year is how many customers say they now expect EU pesticide compliance as table stakes, not a bonus. Sensible.

Process flow (materials → methods → testing)

  • Materials: Paeonia lactiflora Pall. root (Radix Paeoniae Alba), peeled and sun-dried.
  • Extraction: milling → water/food-grade ethanol extraction → filtration → membrane polish → vacuum concentration → spray drying → blend to spec.
  • Testing: paeoniflorin by HPLC; heavy metals by ICP-MS; residual solvents per USP <467>; micro per USP <61>/<62>; pesticides per EU 396/2005 multi-residue GC-MS/MS/LC-MS/MS.
  • Service life: ≈24 months unopened; store ≤25°C, dry, protected from light.
  • Industries: nutraceutical, TCM dosage forms, functional beverages, and cosmetics (calming/brightening). Real-world use may vary by market rules.

Technical specifications

Botanical source Paeonia lactiflora Pall. (Radix Paeoniae Alba)
Plant part Root (peeled, dried)
Marker / assay Paeoniflorin ≥10% HPLC (custom: 20–30% on request)
Solvent system Water + food-grade ethanol
Appearance Light brown to off-white powder (≈ depends on crop)
Particle size 80–120 mesh
Loss on drying ≤5% (105°C)
Heavy metals Pb ≤2 ppm; As ≤1 ppm; Cd ≤1 ppm; Hg ≤0.1 ppm (ICP-MS)
Microbial TAMC ≤1,000 CFU/g; TYMC ≤100 CFU/g; E. coli/Salm. absent
Pesticides Complies EU 396/2005 multi-residue
Residual solvents USP <467>: Class 1 ND; ethanol ≤5,000 ppm
Shelf life / pack 24 months; 25 kg fiber drum (double PE), 1 kg foil for samples

Typical batch snapshot (example): paeoniflorin 12.3% (HPLC), moisture 3.5%, Pb 0.8 ppm, total aerobic count 410 CFU/g. It seems stable, but always verify your own QC.

Applications: how teams actually use it

  • Capsules/tablets: 250–500 mg of 10% Paeonia Extract per serving, often paired with licorice or angelica.
  • Granules/tea sachets: flavor-masked blends; watch hygroscopicity.
  • Topicals: 0.2–2% Paeonia Extract in serums, toners, creams; ISO 16128-friendly.
  • Beverages: clear solutions need extra polishing—pilot it first.

Customer feedback? Many customers say skin feel is “calmer by week two.” Not clinical, but consistent.

Vendor comparison (quick glance)

Vendor Origin Assay (paeoniflorin) Certifications MOQ Lead time Notes
HEX Herbal Medicine Hebei, China ≥10% (typical 12–15%) ISO 22000, ISO 9001, HACCP 1 kg ≈7–10 days Custom 20–30%; clean solvent
EU Trader EU/China 5–10% FSSC 22000 5 kg 2–3 weeks Strong cosmetic focus
US Nutraceutical US (import) 10% standardized cGMP, NSF 25 kg 1–2 weeks ex-warehouse Faster logistics, higher price

Customization and logistics

Options include 10–30% Paeonia Extract, 60–120 mesh milling, ethanol-only or water-only process (where required), and maltodextrin-free lots. Usual pack is 25 kg fiber drum; samples ship in 1 kg foil. Lead times are sane unless harvest swings—book early in Q3, I’d say.

Case notes from the field

  • Indie serum brand: 1% Paeonia Extract with panthenol; internal 28-day panel (n=35) reported −22% perceived redness. Not a clinical trial, but compelling.
  • Supplement house: 300 mg of 10% Paeonia Extract per capsule; reviews mention “monthly comfort.” Obviously, results vary and claims must follow local regs.

Compliance landscape

Built to align with ChP Radix Paeoniae Alba monograph, USP Herbal Medicines Compendium methods for marker assays, ISO 22000 food safety systems, and cosmetic GMP (ISO 22716) where applicable. Always align your label claims with destination-market rules.

References

  1. Chinese Pharmacopoeia (ChP) – Radix Paeoniae Alba monograph
  2. USP Herbal Medicines Compendium – General methods for HPLC marker assays
  3. EU Regulation No 396/2005 – Pesticide residues
  4. ISO 22000 – Food safety management systems


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